UA040082 VEGF-121 Protein, Human
- 公司名稱 杭州斯達(dá)特生物科技有限公司
- 品牌 Starter/斯達(dá)特
- 型號 UA040082
- 產(chǎn)地 江蘇 南京
- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時間 2025/7/16 7:46:53
- 訪問次數(shù) 56
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VEGF-121, an abundant splicing isoform of vascular endothelial growth factor (VEGF), exists as a disulfide-linked homodimer. It induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Contrast to other isoforms, VEGF-121 has very little affinity for heparin-sulfate proteoglycans, without recruiting Neuropilin1-expressing monocytes (NEMs), conferring to VEGF-121 the ability to diffuse freely, and increase tumor growth rate in vivo.