Z02892 PDGF-BB, Human
| 參考價 | ￥1200.00-￥21600.00 |
- 公司名稱 漠寶（廈門）生物科技有限公司
- 品牌GenScript/金斯瑞
- 型號Z02892
- 所在地廈門市
- 廠商性質(zhì)代理商
- 更新時間2025/7/22 11:46:43
- 訪問次數(shù) 21
| 10 μg | 1200.00元 | 1 件可售 |
| 1 mg | 21600.00元 | 1 件可售 |
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9min快速濕轉(zhuǎn)儀，10min蛋白染色儀，全自動WB系統(tǒng)，預(yù)制膠，WB試劑，Protein A/Ni-NTA/Glutathione/Anti-His/Anti-flag Resin，磁珠，ECL發(fā)光試劑，血清，細(xì)胞，培養(yǎng)基，凋亡檢測試劑盒，細(xì)胞活力or增殖檢測試劑盒，細(xì)胞熒光染料，抗體，ELISA試劑盒，重組蛋白，真正無毒核酸染料，瓊脂糖，qPCR Mix，RT-PCR mix，質(zhì)粒，外泌體解決方案，CRISPR/Cas9試劑等
| 供貨周期 | 一周 | 貨號 | Z02892 |
|---|---|---|---|
| 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,食品/農(nóng)產(chǎn)品,生物產(chǎn)業(yè),制藥/生物制藥 | 主要用途 | 由四種不同PDGF亞基形成的五種二聚體之一 |
Platelet-Derived Growth Factor-BB (PDGF-BB) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. In vivo, PDGF-BB is mainly produced in heart and placenta, and predominantly expressed by osteoblasts, fibroblasts, smooth muscle cells, and glial cells. An inactive precursor of PDGF-BB is produced in the endoplasmic reticulum and then activated by a proprotein convertase after secretion. PDGF-BB functions in a paracrine manner and promotes organogenesis, human skeletal development, and wound healing. PDGF-BB also promotes angiogenesis, particularly in the presence of Fibroblast Growth Factor basic. Therefore, PDGF-BB and its related pathways are potential pharmacological targets.
產(chǎn)品簡介
Species ：Human
Protein Construction ：Expressed with an N-terminal Met.PDGF-BB (Ser82-Thr190)
Accession # P01127
Purity： > 97% as analyzed by SDS-PAGE
> 97% as analyzed by HPLC
Endotoxin Level： < 1 EU/μg of protein by LAL method
Biological Activity ：Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 3.0 ng/ml, corresponding to a specific activity of > 3.3 × 105 IU/mg.
Expression System： E. coli
Theoretical Molecular Weight ：24.8 kDa
Formulation： Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Reconstitution ：It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
Storage & Stability： Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.
技術(shù)背景
Target Background ：Platelet-Derived Growth Factor-BB (PDGF-BB) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. In vivo, PDGF-BB is mainly produced in heart and placenta, and predominantly expressed by osteoblasts, fibroblasts, smooth muscle cells, and glial cells. An inactive precursor of PDGF-BB is produced in the endoplasmic reticulum and then activated by a proprotein convertase after secretion. PDGF-BB functions in a paracrine manner and promotes organogenesis, human skeletal development, and wound healing. PDGF-BB also promotes angiogenesis, particularly in the presence of Fibroblast Growth Factor basic. Therefore, PDGF-BB and its related pathways are potential pharmacological targets.
Synonyms ：PDGFBB; IBGC5; PDGF-2; PDGF2; SIS; SSV; c-sis; platelet derived growth factor subunit B
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
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