Synonym:

Diferuloylmethane, Diferulylmethane, Natural Yellow 3, （E,E）-1,7-bis（4-Hydroxy-3-methoxyphenyl）-1,6-heptadiene-3,5-dione

CAS Number:

458-37-7

Linear Formula:

[HOC₆H₃（OCH₃）CH=CHCO]₂CH₂

Molecular Weight:

368.38

Colour Index Number:

75300

Beilstein Registry Number:

2306965

EC Number:

207-280-5

MDL number:

MFCD00008365

PubChem Substance ID:

24892983

Biochem/physiol Actions

A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C （PKC） activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase （iNOS）, cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

vapor density

13 （vs air）

assay

≥80% （Curcumin）

≥94% （curcuminoid content）

solubility

ethanol: 1 mg/mL

DMSO: 11 mg/mL

0.5 M NaOH: soluble （then immediay diluted in PBS）

Gene Information

human ... APP（ 351 ）, CYP1A2（ 1544 ）

storage temp.

−20°C

Hazard Codes

Xi

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

2

RTECS

MI5230000

品名

產(chǎn)地

貨號

規(guī)格

單價

備注

Curcumin 姜黃素

Sigma

C7727

250MG

詢價

現(xiàn)貨

Curcumin 姜黃素

Sigma

C7727

500MG

詢價

現(xiàn)貨

Curcumin 姜黃素

Sigma

C7727

1G

詢價

現(xiàn)貨