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CBP10408 | |
| Format | Genomic DNA |
| Description | EGFR L858R lies within the protein kinase domain of the Egfr protein (UniProt.org). L858R results in increased kinase activity, is transforming in cell culture (PMID: 29533785), and promotes tumor formation in mouse models (PMID: 16187797). |
| Technical Data | |
| DNA Change | c.2573T>G |
| AA Change | p.L858R |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | ENST00000275493 |
| Cosmic ID | COSM6224 |
| Chr position(GRCh37) | chr7:55259515 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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