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Source

Rabbit

Applications

WB,IF,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Actinin-α3 Polyclonal Antibody detects endogenous levels of Actinin-α3 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human ACTN3. AA range:1-50

Uniprot No

Q08043

Alternative names

ACTN3; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

actinin alpha 3 (gene/pseudogene)(ACTN3) Homo sapiens This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. [provided by RefSeq, Feb 2014],

Other

ACTN3, Alpha-actinin-3

Mol.Wt (Da)

103294

Concentration

1 mg/ml