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上海允麥生物科技有限公司
中級(jí)會(huì)員·7年
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Recombinant human XRN1
XRN1_HUMAN; Dhm2; mXRN1; SEP1; Strand-exchange protein 1 homolog; 5'-3' exoribonuclease 1.
濃度：1mg/ ml
來(lái)源：Recombinant Human
純度：≥95% SDS-PAGE
表達(dá)系統(tǒng)：Escherichia coli
標(biāo)簽：His tag
蛋白長(zhǎng)度：Full length protein
內(nèi)毒素水平：<1.000 Eu/µg
純化方法：HPLC
應(yīng)用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保質(zhì)期：1年
Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A-type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eukaryotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, MANI, three isoforms of lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta and the nucleoplasmic protein LAP 2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. LAP 2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent- and salt-resistant nucleoskeletal structure.
多克隆抗體
產(chǎn)品名稱：Rabbit Anti-XRN1 antibody
Rabbit Anti-XRN1
別名：XRN1_HUMAN; Dhm2; mXRN1; SEP1; Strand-exchange protein 1 homolog; 5'-3' exoribonuclease 1.
來(lái)源：Rabbit
克隆類型：Polyclonal
濃度：1mg/ml
亞型：IgG
反應(yīng)：Human,Mouse,Horse, Cow, Dog, Chimpanzee, Rhesus monkey, Orangutan
應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
理論分子量：193kDa
免疫原：KLH conjugated synthetic peptide derived from human XRN1
保存：-20℃
保質(zhì)期：1年
單克隆抗體
產(chǎn)品名稱：Anti-XRN1 antibody
Mouse Anti-XRN1
別名：XRN1_HUMAN; Dhm2; mXRN1; SEP1; Strand-exchange protein 1 homolog; 5'-3' exoribonuclease 1.
來(lái)源：Mouse
克隆類型：Monoclonal
濃度：1mg/ml
亞型：IgG
反應(yīng)：Human
應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應(yīng): Human
理論分子量：193kDa
免疫原：KLH conjugated synthetic peptide derived from human XRN1
保存：-20℃
保質(zhì)期：1年
This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.
