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陜西新研博美生物科技有限公司>技術(shù)文章>945928-17-6,5-羧基四甲基羅丹明-炔烴的化學(xué)特性

技術(shù)文章

945928-17-6,5-羧基四甲基羅丹明-炔烴的化學(xué)特性

閱讀:598          發(fā)布時(shí)間:2022-1-13

中文名稱:5-羧基四甲基羅丹明-炔烴

      5-四甲基羅單明炔基化物

其它名稱5-TAMRA alkyne 

      5-Carboxytetramethylrhodamine-Alkyne

CAS NO:945928-17-6

分子式:C28H25N3O4

分子量:467.52 g/mol

溶解性:Soluble in DMSO

含 量:95%+

外 觀:固體粉末

保存方法:-20避光避濕

Ex/Em:555/575

結(jié)構(gòu)式:



產(chǎn)品簡介:The red-fluorescent tetramethylrhodamine alkyne can be reacted with azides via a copper-catalyzed click reaction. Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure. The two-step reaction procedure involves a copper-catalyzed triazole formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme temperatures or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur – the label and detection tags react selectively and specifically with one another. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls – functional groups that are not unique – click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.




 


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