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Fibroblast Growth Factor-basic （FGF-basic）, also known as FGF-2, is a highly conserved protein consisting of 145 amino acids. It belongs to the fibroblast growth factor family and is known for its potent mitogenic and angiogenic properties. FGF-basic plays a crucial role in various cellular processes, including cell proliferation, differentiation, and tissue regeneration. It exerts its biological effects by binding to FGF receptors and activating downstream signaling pathways, such as the MAPK/ERK and PI3K/Akt pathways. Due to its ability to stimulate cell growth and promote angiogenesis, FGF-basic has been extensively studied for its therapeutic potential in tissue repair, wound healing, and regenerative medicine.