英文名稱lysozyme

中文名稱溶菌酶抗體

別    名1 4 beta n acetylmuramidase c; 14 beta N acetylmuramidase; 14 beta N acetylmuramidase C; EC 3.2.1.17; lysosyme; Lysozyme C; Lysozyme C precursor; Lyz; LZM; Muramidase.  

研究領(lǐng)域

抗體來源Rabbit

克隆類型Polyclonal

交叉反應(yīng)Chicken, 

產(chǎn)品應(yīng)用ELISA=1:500-1000 IHC-F=1:100-500 （石蠟切片需做抗原修復(fù)）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量17kDa

細胞定位分泌型蛋白 

性    狀Liquid

濃    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from chicken lysozyme:51-150/211 

亞    型IgG

純化方法affinity purified by Protein A

儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

產(chǎn)品介紹Lysozyme catalyzes the hydrolysis of certain mucopolysaccharides of bacterial cell walls. Specifically, it catalyzes the hydrolysis of the bacterial cell wall beta glycosidic linkages between N acetylmuramic acid and N acetylglucosamine. It is found in spleen, lung, kidney, white blood cells, plasma, saliva, milk, and tears.

Subcellular Location:

Secreted.

DISEASE:

Defects in LYZ are a cause of amyloidosis type 8 (AMYL8) [MIM:105200]; also known as systemic non-neuropathic amyloidosis or Ostertag-type amyloidosis. AMYL8 is a hereditary generalized amyloidosis due to deposition of apolipoprotein A1, fibrinogen and lysozyme amyloids. Viscera are particularly affected. There is no involvement of the nervous system. Clinical features include renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash.

Similarity:

Belongs to the glycosyl hydrolase 22 family.

SWISS:

P61626

Gene ID:

396218

Database links:

Entrez Gene: 396218 Chicken

SwissProt: P00698 Chicken

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.