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英文名稱  Anti-CUTC 
中文名稱   
別    名  CGI 32; CGI32; Copper homeostasis protein cutC homolog; cutC; CutC copper transporter homolog (E. coli); CUTC_HUMAN; RP11-483F11.3. 
濃    度  1mg/1ml 
規(guī) 格  0.2ml/200μg    
抗體來源  Rabbit  
克隆類型  polyclonal 
交叉反應(yīng)  Human, Mouse, Rat  
產(chǎn)品類型  一抗    
研究領(lǐng)域  腫瘤 細(xì)胞生物 轉(zhuǎn)運(yùn)蛋白 新陳代謝  
蛋白分子量  predicted molecular weight: 29kDa 
性    狀  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human CUTC 
亞    型  IgG 
純化方法  affinity purified by Protein A 
儲(chǔ) 存 液  Preservative: 15mM Soium zde, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
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產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
（石蠟切片需做抗原修復(fù)） 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
產(chǎn)品介紹 Copper is an essential micronutrient used as a co-factor for several essential enzymes in all living organisms. Due to the high toxicity of copper, its metabolism is tightly regulated and defects in this regulation can cause Menkes (deficiency) or Wilson (accumulation) disease in various tissue. CUTC (cutC copper transporter homolog (E. coli)), also known as CGI-32, is a 273 amino acid protein belonging to the cutC family. CUTC is involved in copper homeostasis and is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.
Function : May play a role in copper homeostasis. Can bind one Cu(1+) per subunit.
Subunit : Homotetramer. 
Subcellular Location : Cytoplasm. Nucleus. The overexpressed protein is detected in the cytoplasm, and depending on the cell line, also in the nucleus.
Tissue Specificity : Ubiquitous.
Similarity : Belongs to the CutC family.
Database links : UniProtKB/Swiss-Prot: Q9NTM9.1
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