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化工儀器網(wǎng)>產(chǎn)品展廳>試劑標物>生化試劑>抗體/抗原>S0B1548 FITC Rabbit Anti-Human CD86 Antibod...

S0B1548 FITC Rabbit Anti-Human CD86 Antibody (S-990-1)

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  • 公司名稱 杭州斯達特生物科技有限公司
  • 品牌 Starter/斯達特
  • 型號 S0B1548
  • 產(chǎn)地 浙江 杭州
  • 廠商性質(zhì) 生產(chǎn)廠家
  • 更新時間 2025/8/6 17:30:48
  • 訪問次數(shù) 52

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杭州斯達特是一家集研發(fā)、生產(chǎn)、銷售與技術(shù)服務(wù)為一體的高科技生物公司,志在為全球生物醫(yī)學(xué)研究、體外診斷企業(yè)、生物制藥企業(yè)提供優(yōu)質(zhì)的抗體、蛋白、試劑盒和定制服務(wù),包括科研抗體、CDx和IVD抗原和抗體原料、一步法ELISA試劑盒、鼠兔通用二抗試劑盒以及其他用途的免疫試劑整體解決方案。


公司核心團隊深耕抗體研發(fā)十五年,具有成功開發(fā)數(shù)千種精準醫(yī)學(xué)抗體、科研抗體的豐富經(jīng)驗。公司建立了多物種單B細胞抗體開發(fā)平臺(兔單抗,鼠類單抗等)、傳統(tǒng)鼠單抗、重組蛋白表達平臺及完善的抗體應(yīng)用驗證和檢測體系(包括免疫層析,酶聯(lián)免疫,流式分析,免疫組化,免疫印跡,免疫熒光,免疫沉淀等)。已正式通過歐盟98/79/EC認證、ISO9001認證和ISO13485認證。


公司以加速人類、疾病診斷、為人類和動物健康保駕護航為使命,以扎實的科學(xué)技術(shù)為基礎(chǔ),秉承向正向善向上的價值觀,以行業(yè)客戶需求為導(dǎo)向,愿與全球同仁精誠合作,共啟健康新篇章。


斯達特,專注于抗體研發(fā)和制造,您的最佳抗體優(yōu)選伙伴。

抗體,蛋白,試劑盒

CD86 protein, also known as B7.2, is a crucial cell surface membrane protein belonging to the immunoglobulin superfamily with a molecular weight of approximately 80Kd. It is highly expressed on the surface of antigen-presenting cells. CD86 is expressed in various immune cells, including dendritic cells, monocytes, memory T lymphocytes, germinal center B lymphocytes, activated B lymphocytes, and activated T lymphocytes. CD86 protein plays a pivotal role in the immune system by interacting with CD28 and CTLA-4 (also known as CD152) proteins on the surface of T cells. The binding of CD86 to CD28 serves as a co-stimulatory signal for T cell activation, while the interaction between CD86 and CTLA-4 negatively regulates T cell activation and reduces immune responses. Additionally, CD86 protein contains two extracellular immunoglobulin domains (IgV and IgC), which bind to intercellular adhesion molecule 1 (ICAM-1) and participate in immune cell contact and signal transduction. Abnormal expression of CD86 is closely associated with the occurrence and development of various immune-related diseases. Therefore, understanding the structure and function of CD86 protein is crucial for revealing its immune regulatory mechanisms and providing new theoretical bases for disease treatment. Furthermore, experimental studies have demonstrated that CD86 protein plays a significant role in the activation and differentiation of immune cells, holding potential therapeutic value in immune-related diseases and offering a new breakthrough in the study of immune regulatory mechanisms.



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