S0B5041 Rabbit Anti-Human TCR delta Antibody (S-1504-45)
- 公司名稱(chēng) 杭州斯達(dá)特生物科技有限公司
- 品牌 Starter/斯達(dá)特
- 型號(hào) S0B5041
- 產(chǎn)地 浙江 杭州
- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時(shí)間 2025/8/7 11:22:22
- 訪問(wèn)次數(shù) 52
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The TCR delta chain is a crucial component of the γδ T cell receptor (TCR), forming a heterodimer with the TCR gamma chain. This TCRγδ complex is primarily expressed on the surface of γδ T cells and is capable of recognizing a diverse range of antigens, including non-peptide small molecules and glycolipids. Unlike αβ T cells, the TCR delta chain generates diversity through V(D)J recombination, but it has a relatively small gene repertoire and lacks the capacity for somatic hypermutation. The TCRγδ complex associates with the CD3 complex to form an octameric structure, which is involved in T cell activation and signaling. γδ T cells possess both adaptive and innate immune characteristics, allowing them to rapidly respond to pathogen infections, tumor growth, and tissue damage.
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