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HMGBiotech 是一家生物技術(shù)公司，由 HMGB 領(lǐng)域的科學(xué)家 Marco E. Bianchi 創(chuàng)立。HMGBiotech srl 為活躍在這個充滿希望的領(lǐng)域的其他研究人員和公司提供試劑，服務(wù)和想法。它還有助于Bianchi實驗室開發(fā)分析和試劑。
HMGB1是細胞核的組成部分，在基因組的組織和表達中具有多種功能。當(dāng)細胞因損傷（病毒、機械或化學(xué)創(chuàng)傷、中毒）而死亡時，HMGB1被釋放并被附近細胞中的受體吸收。此外，處于嚴重壓力下的細胞甚至在死亡之前也會分泌HMGB1 。存活的細胞會產(chǎn)生一線反應(yīng)——炎癥——并嘗試替換死細胞并重建受損組織。HMGB1 促進恢復(fù)和再生，例如梗塞后的心臟。然而，過多的HMGB1與敗血癥（過度炎癥導(dǎo)致急性痛苦并最終死亡）、關(guān)節(jié)炎、動脈粥樣硬化和癌癥轉(zhuǎn)移有關(guān)。
HMGBiotech srl 為活躍在這個有前途的領(lǐng)域的其他研究人員和公司提供試劑、服務(wù)和想法。它還幫助 Bianchi 實驗室開發(fā)檢測方法和試劑。
HMGBiotech在意大利米蘭 via Olgettina 58, 20133 的 OSR 內(nèi)設(shè)有研發(fā)和生產(chǎn)部門。
上海起發(fā)HMGBiotech2022年價格表
| 貨號 | 品名 | 規(guī)格 | 價格 | 品牌 |
| HM-001 | Control cell lysates from Hmgb1 +/+ | ea | 240 | hmgbiotech |
| HM-002 | Control cell lysates from Hmgb1 -/- | ea | 480 | hmgbiotech |
| HM-011 | 25 µg BoxA from HMGB1, LPS-free and tested in migration assay | 25 µg | 2400 | hmgbiotech |
| HM-012 | 100 µg BoxA from HMGB1, LPS-free and tested in migration assay | 100 µg | 4600 | hmgbiotech |
| HM-013 | 500 µg BoxA from HMGB1, LPS-free and tested in migration assay | 500 µg | 9270 | hmgbiotech |
| HM-014 | 2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay | 2.5 mg | 28440 | hmgbiotech |
| HM-030 | HMGB1 Isoforms Kit – Test size | Kit | 6120 | hmgbiotech |
| HM-031 | HMGB1 Isoforms Kit – Regular size | Kit | 18720 | hmgbiotech |
| HM-050 | 1 mg BoxB from HMGB1, LPS-free and tested in migration assay | 1 mg | 18720 | hmgbiotech |
| HM-051 | 250 µg BoxB from HMGB1, LPS-free and tested in migration assay | 250 µg | 6120 | hmgbiotech |
| HM-052 | 100 µg BoxB from HMGB1, LPS-free and tested in migration assay | 100 µg | 4600 | hmgbiotech |
| HM-053 | 15 µg BoxB from HMGB1, LPS-free and tested in migration assay | 15 µg | 2400 | hmgbiotech |
| HM-062 | 50 µg Terminally oxdized HMGB1, LPS free | 50 µg | 8730 | hmgbiotech |
| HM-061 | 100 µg Terminally oxdized HMGB1, LPS free | 100 µg | 13410 | hmgbiotech |
| HM-060 | 250 µg Terminally oxdized HMGB1, LPS free | 250 µg | 17640 | hmgbiotech |
| HM-100 | 1 mg HMGB1 for biochemistry | 1 mg | 16740 | hmgbiotech |
| HM-101 | 250 µg HMGB1 for biochemistry | 250 µg | 7380 | hmgbiotech |
| HM-114 | 500 µg Fully reduced HMGB1, LPS free | 500 µg | 17640 | hmgbiotech |
| HM-115 | 100 µg Fully reduced HMGB1, LPS free | 100 µg | 6840 | hmgbiotech |
| HM-116 | 50 µg Fully reduced HMGB1, LPS free | 50 µg | 4800 | hmgbiotech |
| HM-117 | 15 µg Fully reduced HMGB1, LPS free | 15 µg | 2400 | hmgbiotech |
| HM-120 | 250 µg Disulfide HMGB1, LPS free | 250 µg | 17640 | hmgbiotech |
| HM-121 | 100 µg Disulfide HMGB1, LPS free | 100 µg | 13410 | hmgbiotech |
| HM-122 | 50 µg Disulfide HMGB1, LPS free | 50 µg | 8730 | hmgbiotech |
| HM-123 | 10 µg Disulfide HMGB1, LPS free | 10 µg | 2900 | hmgbiotech |
| HM-130 | 500 µg Non-oxidizable HMGB1, LPS free | 500 µg | 17640 | hmgbiotech |
| HM-131 | 100 µg Non-oxidizable HMGB1, LPS free | 100 µg | 6840 | hmgbiotech |
| HM-132 | 50 µg Non-oxidizable HMGB1, LPS free | 50 µg | 4800 | hmgbiotech |
| HM-133 | 15 µg Non-oxidizable HMGB1, LPS free | 15 µg | 2400 | hmgbiotech |
| HM-151 | 500 µg HMGB2, LPS-free and tested in migration assay | 500 µg | 17640 | hmgbiotech |
| HM-152 | 100 µg HMGB2, LPS-free and tested in migration assay | 100 µg | 6840 | hmgbiotech |
| HM-153 | 50 µg HMGB2, LPS-free and tested in migration assay | 50 µg | 4800 | hmgbiotech |
| HM-160 | 5 µg SDF-1α (CXCL12) labelled 15N and 13C for NMR | 5 µg | 5130 | hmgbiotech |
| HM-161 | 50 µg SDF-1α (CXCL12) labelled 15N and 13C for NMR | 50 µg | 29880 | hmgbiotech |
| HM-162 | 50 µg SDF-1α (CXCL12) labelled 15N for Mass Spectometry or NMR | 50 µg | 29880 | hmgbiotech |
| HM-163 | 5 µg SDF-1α (CXCL12) labelled 15N for Mass Spectometry or NMR | 5 µg | 5130 | hmgbiotech |
| HM-170 | 250 µg Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | 250 µg | 16380 | hmgbiotech |
| HM-171 | 100 µg Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | 100 µg | 12420 | hmgbiotech |
| HM-172 | 50 µg Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | 50 µg | 8100 | hmgbiotech |
| HM-173 | 15 µg Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | 15 µg | 2700 | hmgbiotech |
| HM-180 | 50 µg HMGB1 15N labelled for Mass Spectrometry | 50 µg | 29880 | hmgbiotech |
| HM-181 | 5 µg HMGB1 15N labelled for Mass Spectrometry | 5 µg | 5130 | hmgbiotech |
| HM-190 | 2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay | 2.5 mg | 28440 | hmgbiotech |
| HM-191 | 500 µg BoxA 2D from HMGB1, LPS-free and tested in migration assay | 500 µg | 9270 | hmgbiotech |
| HM-192 | 100 µg BoxA 2D from HMGB1, LPS-free and tested in migration assay | 100 µg | 4600 | hmgbiotech |
| HM-193 | 25 µg BoxA 2D from HMGB1, LPS-free and tested in migration assay | 25 µg | 2400 | hmgbiotech |
| HM-201 | Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells | ea | 15750 | hmgbiotech |
| HM-221 | Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells | ea | 15750 | hmgbiotech |
| HM-223 | Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and one vial of HM-221 wt cells | ea | 15750 | hmgbiotech |
| HM-251 | Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells | ea | 15750 | hmgbiotech |
| HM-300 | 20 µg p-mHMG1 | 20 µg | 3150 | hmgbiotech |
| HM-301 | 20 µg p-mHMG1tag | 20 µg | 3150 | hmgbiotech |
| HM-302 | 20 µg pEGFP-HMGB1 | 20 µg | 3150 | hmgbiotech |
| HM-310 | 20 µg pcDNA/FL-RAGE plasmid | 20 µg | 3150 | hmgbiotech |
| HM-311 | 20 µg pcDNA/esRAGE plasmid | 20 µg | 3150 | hmgbiotech |
| HM-312 | 20 µg pcDNA/FL-RAGE-myc plasmid | 20 µg | 3150 | hmgbiotech |
| HM-901 | 50 µg DPH1.1 anti HMGB1 monoclonal antibody | 50 µg | 5000 | hmgbiotech |
| HM-902 | 250 µg DPH1.1 anti HMGB1 monoclonal antibody | 250 µg | 15120 | hmgbiotech |
| HM-903 | 1 mg DPH1.1 anti HMGB1 monoclonal antibody | 1 mg | 35100 | hmgbiotech |
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