Recombinant Human Beta 2 Microglobulin, His Tag
人β2微球蛋白  （B2M His）
Catalogue Number  PRO-859

Synonyms:
Beta-2-microglobin, Beta chain of MHC class I molecules, B2M, Beta 2 Microglobulin. 

Introduction:
B2M is a part of the MHC class I family that participates in the presentation of peptide antigens to the immune system. B2M is localized on the surface of numerous cells and abundant on the surface of white blood cells. High production or destruction of these cells causes B2M levels in the blood to raise. This increase is observed in people with cancers involving white blood cells, but it is mainly significant in people newly diagnosed with multiple myeloma. B2M Testing is done primarily when evaluating a person for certain kinds of cancer affecting white blood cells including chronic lymphocytic leukemia, non-Hodgkin''s lymphoma, and multiple myeloma or kidney disease. 

Description:
B2M Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids （1-119 a.a.） and having a molecular mass of 14 kDa. The B2M is fused to 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. 

Source:
Escherichia Coli. 
Physical Appearance  Sterile filtered colorless solution. 

Formulation:
B2M Human solution containing 20mM Trsi pH-8, 2mM DTT, 0.1M NaCl & 20% glycerol. 

Stability:
B2M Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles. 

Purity:
Greater than 95.0% as determined by SDS-PAGE. 

Amino acid sequence:
MGSSHHHHHH SSGLVPRGSH MIQRTPKIQV YSRHPAENGK SNFLNCYVSG FHPSDIEVDL LKNGERIEKV EHSDLSFSKD WSFYLLYYTE FTPTEKDEYA CRVNHVTLSQ PKIVKWDRDM. 

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. 
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